A new patient has just been admitted with multiple orders. Which order should the nurse perform first?

Administering insulin subcutaneously should be the nurse's first action in this scenario due to its critical role in maintaining the patient's metabolic stability, particularly if there is a known history of diabetes or elevated blood sugar levels. Insulin's effects are rapid, and timely administration can prevent the serious consequences of hyperglycemia, such as diabetic ketoacidosis or hyperglycemic hyperosmolar state. Immediate attention to blood sugar levels is essential for the safety and well-being of the patient, especially if the admission is due to concerns about metabolic or glucose management.

In contrast, while other tasks like checking vital signs, administering antibiotics, and collecting laboratory samples are important, they generally do not present the same level of immediate risk to the patient's safety. Vital signs provide ongoing patient assessment but do not require immediate action like insulin can. The administration of amoxicillin is important for addressing potential infections, but antibiotic stewardship often allows for a short delay, especially if there is no immediate threat to the patient’s condition. Similarly, while collecting lab tests is crucial for diagnosis and treatment planning, these can often be done after addressing any immediate critical needs, such as administering insulin.