Which of the following is NOT a manifestation of carbon monoxide poisoning?

In the context of carbon monoxide poisoning, chest pain is not traditionally recognized as a common manifestation. Carbon monoxide (CO) binds preferentially to hemoglobin, forming carboxyhemoglobin, which leads to a deficiency in oxygen delivery to tissues. The primary symptoms associated with CO poisoning typically include headache, dizziness, and altered mental status due to the brain’s high sensitivity to reduced oxygen levels.

Headache is an early and common symptom of CO poisoning, often described as a dull or throbbing pain. Dizziness can arise from compromised oxygenation to the brain, leading to lightheadedness or a feeling of being faint. Altered mental status can occur as the brain experiences hypoxia, resulting in confusion, agitation, or even loss of consciousness.

Chest pain, although it can be a symptom associated with other cardiopulmonary conditions, is less directly linked to CO exposure compared to the other listed symptoms. Therefore, the selection of this option as not being a manifestation reflects an understanding of the specific pathophysiological consequences of carbon monoxide exposure.